Senior Medical Director

Ventyx Biosciences, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative oral medicines for patients living with autoimmune and inflammatory disorders. We believe our ability to efficiently discover and develop differentiated drug candidates will allow us to address important unmet medical needs with novel oral therapies that shift the immunology markets from injectables to oral drugs. Our current pipeline includes four clinical-stage programs targeting TYK2, S1P1R and NLRP3, thereby positioning us to become a leader in the development of oral immunology drugs. Join this team of life science professionals to bring this portfolio of programs to fruition.

Job Summary 

The Medical Director/Senior Medical Director will help develop multiple Ventyx Clinical and Medical assets by supporting the successful execution of clinical development programs and deliverables. This key position will assist with program development activities across the Ventyx portfolio. The successful individual will effectively collaborate cross functionally with teams and develop strong partnerships both internally and across external KOLs, vendors, academicians, and collaboration partners in driving the development of Ventyx assets. This role plays a key part in designing and executing clinical trials, creating medical and scientific documents, evaluating safety, and contributing to data analyses to bring new best in class medicines to patients.

The incumbent will work closely with colleagues in clinical development, program leadership, biometrics, clinical operations, safety/pharmacovigilance, regulatory, and translational research.

Roles and Responsibilities 

• Establishes and approves scientific methods for design and implementation of applicable clinical protocols, data collection systems, and final reports.
• Participates and leads clinical sub teams in the design, execution, and reporting of Company-sponsored worldwide clinical trials programs, including clinical trial strategy and plans, overall study design, protocols, and the identification of suitable investigators and consultants.
• Oversees medical monitoring for and responding to safety events. Provides medical expertise ensuring the safety of the products and patients, including SAE evaluation and reporting.
• Works in close collaboration with operations personnel; including the selection and management of CRO activities.
• Utilize medical experience and understanding to guide the clinical development process providing teams with insights related to diseases treatment and therapies.
• Potentially responsible for managing therapeutic area physicians and clinical scientists.
• Evaluates efficacy data; summarizes data for senior management or outside parties.
• Interfaces with regulatory agencies for clinical development programs and regulatory submissions.
• Oversees the interaction with medical consultants, some clinical advisors, and investigators; serves to influence and expedite the progression of the clinical studies.
• Participates in the preparation of protocols, Investigator Brochures, clinical study reports, safety reports, and the clinical sections of Annual Reports, INDs/IMPDs, NDAs/MAAs, SOPs, abstracts, manuscripts, and other medical documents.
• Evaluates and advises on business development and market opportunities from a medical perspective.
• Provides clinical expertise to the drug discovery teams involved in the clinical candidate selection process.
• Helps conceptualize, strategize, establish and coordinate Ventyx’s clinical trial activities in TA.
• Additional duties assigned as needed.

Qualifications and Experience

• MD or international equivalent required.
• 3-5 years clinical research experience in a pharmaceutical, biotech, or CRO environment. Preferably with experience in immune-mediated inflammatory diseases.
• Working knowledge of the drug development process.
• Demonstrated agility to learn, and prioritize multiple responsibilities independently, remove barriers and drive projects to completion.
• Strong oral & written scientific communications skills.
• Good presentation skills for diverse audiences (investigator meetings, site personnel, KOL interactions and internal project teams).
• Ability to strike a balance between independent work and team interaction, be a team player in a cross-functional team.
• Well-developed interpersonal skills, with experience in interacting with and influencing people, building strong positive relationships.
• Proficiency in Microsoft Office and other productivity tools with an aptitude to learn new software and systems.
• Ability to travel as needed.